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Income Taxes - Additional Information (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Operating Loss Carryforwards [Line Items]      
Federal operating loss carryforwards $ 254,500    
State operating loss carryforwards 218,000    
Foreign operating loss carryforwards 1,300    
Federal loss carryforwards 248,100    
Research and development credit carryforwards $ 22,210 $ 12,930  
Operating loss and research and development credit carryforwards, limitations on use These ownership changes may limit the amount of NOL and credit carryforwards that can be utilized to offset future taxable income and income tax, respectively. In general, an “ownership change” as defined by the tax code results from a transaction or series of transactions over a three-year period resulting in an ownership change of more than 50 percent of the outstanding stock of a company by certain stockholders or public groups. During 2020, the Company completed a study to assess whether an ownership change within the meaning of Section 382 had occurred for the time period prior to July 15, 2020.    
Cumulative change in ownership percentage 50.00%    
Decreases in unrecognized tax benefits $ 0 0 $ 0
Accrual for interest or penalties 0 0  
Recognized interest and penalties $ 0 0  
Federal      
Operating Loss Carryforwards [Line Items]      
Operating loss carryforwards, future taxable income, offset percentage 80.00%    
Research and development credit carryforwards $ 8,800 $ 6,100 $ 12,500
Research and development credit carryforwards, begin to expire 2030    
State      
Operating Loss Carryforwards [Line Items]      
State operating loss carryforwards $ 500