Consolidated Statements of Operations and Comprehensive Loss - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Income Statement [Abstract]
Revenues	$ 4,737	$ 1,078	$ 0
Grant revenues	0	0	71
Total revenues	4,737	1,078	71
Operating expenses:
Research and development	130,225	84,255	56,998
General and administrative	42,394	24,525	18,026
Total operating expenses	172,619	108,780	75,024
Loss from operations	(167,882)	(107,702)	(74,953)
Other income (expense):
Interest income	4,317	157	991
Change in fair value of derivative asset	600	0	0
Other income (expense), net	57	(96)	150
Total other income, net	4,974	61	1,141
Loss Before Equity Method Investment, Total	(162,908)	(107,641)	(73,812)
Loss on equity method investment	(1,010)	0	0
Net loss	$ (163,918)	$ (107,641)	$ (73,812)
Earnings Per Share [Abstract]
Basic	$ (3.15)	$ (2.80)	$ (2.42)
Diluted	$ (3.15)	$ (2.80)	$ (2.42)
Basic - Weighted Average	51,982	38,436	30,448
Diluted - Weighted Average	51,982	38,436	30,448
Other comprehensive income (loss):
Unrealized gain (loss) on investment securities	$ (3,549)	$ (407)	$ (123)
Comprehensive net loss	$ (167,467)	$ (108,048)	$ (73,935)