Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Common stock and Paid-In Capital	Accumulated Other Comprehensive Income	Accumulated Deficit
Beginning Balance at Dec. 31, 2020	$ 168,919		$ 336,508	$ 25	$ (167,614)
Beginning Balance, Shares at Dec. 31, 2020		33,001,000
Issuance of common stock, net of transaction costs, shares		4,562,000
Issuance of common stock, net of transaction costs, value	72,558		72,558
Stock issued under Stock Purchase Plan, shares		47,000
Stock issued under Stock Purchase Plan, value	522		522
Vesting of shares subject to repurchase	11		11
Vesting of shares subject to repurchase, shares		8,000
Exercise of stock options	802		802
Exercise of stock options, shares		62,000
Stock-based compensation	7,639		7,639
Comprehensive loss	(15)			(15)
Net loss	(48,996)				(48,996)
Ending Balance at Jun. 30, 2021	201,440		418,040	10	(216,610)
Ending Balance, Shares at Jun. 30, 2021		37,680,000
Beginning Balance at Mar. 31, 2021	149,480		339,976	19	(190,515)
Beginning Balance, Shares at Mar. 31, 2021		33,017,000
Issuance of common stock, net of transaction costs, shares		4,562,000
Issuance of common stock, net of transaction costs, value	72,558		72,558
Stock issued under Stock Purchase Plan, shares		47,000
Stock issued under Stock Purchase Plan, value	522		522
Vesting of shares subject to repurchase	6		6
Vesting of shares subject to repurchase, shares		5,000
Exercise of stock options	745		745
Exercise of stock options, shares		49,000
Stock-based compensation	4,233		4,233
Comprehensive loss	(9)			(9)
Net loss	(26,095)				(26,095)
Ending Balance at Jun. 30, 2021	201,440		418,040	10	(216,610)
Ending Balance, Shares at Jun. 30, 2021		37,680,000
Beginning Balance at Dec. 31, 2021	331,944		607,581	(382)	(275,255)
Beginning Balance, Shares at Dec. 31, 2021		47,597,000
Issuance of common stock, net of transaction costs, shares		5,626,000
Issuance of common stock, net of transaction costs, value	117,242		117,242
Stock issued under Stock Purchase Plan, shares		66,000
Stock issued under Stock Purchase Plan, value	813		813
Vesting of shares subject to repurchase	2		2
Vesting of shares subject to repurchase, shares		1,000
Exercise of stock options	$ 3,517		3,517
Exercise of stock options, shares	429,955	430,000
Stock-based compensation	$ 12,886		12,886
Comprehensive loss	(3,237)			(3,237)
Net loss	(77,002)				(77,002)
Ending Balance at Jun. 30, 2022	386,165		742,041	(3,619)	(352,257)
Ending Balance, Shares at Jun. 30, 2022		53,720,000
Beginning Balance at Mar. 31, 2022	303,044		615,118	(2,192)	(309,882)
Beginning Balance, Shares at Mar. 31, 2022		47,801,000
Issuance of common stock, net of transaction costs, shares		5,626,000
Issuance of common stock, net of transaction costs, value	117,242		117,242
Stock issued under Stock Purchase Plan, shares		66,000
Stock issued under Stock Purchase Plan, value	813		813
Exercise of stock options	1,737		1,737
Exercise of stock options, shares		227,000
Stock-based compensation	7,131		7,131
Comprehensive loss	(1,427)			(1,427)
Net loss	(42,375)				(42,375)
Ending Balance at Jun. 30, 2022	$ 386,165		$ 742,041	$ (3,619)	$ (352,257)
Ending Balance, Shares at Jun. 30, 2022		53,720,000