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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Income Statement [Abstract]        
License revenues $ 439,000 $ 3,570,000
Type of Revenue Extensible List us-gaap:GrantMember us-gaap:GrantMember us-gaap:GrantMember us-gaap:GrantMember
Operating expenses:        
Research and development $ 32,995,000 $ 20,487,000 $ 61,247,000 $ 38,071,000
General and administrative 10,489,000 5,602,000 19,195,000 10,936,000
Total operating expenses 43,484,000 26,089,000 80,442,000 49,007,000
Loss from operations (43,045,000) (26,089,000) (76,872,000) (49,007,000)
Other income (expense):        
Interest income 720,000 23,000 913,000 53,000
Other expense, net (81,000) (29,000) (64,000) (42,000)
Change in valuation of derivative asset 31,000 31,000
Total other expense, net 670,000 (6,000) 880,000 11,000
Loss before equity method investment (42,375,000) (26,095,000) (75,992,000) (48,996,000)
Loss on equity method investment 0 0 (1,010,000) 0
Net loss $ (42,375,000) $ (26,095,000) $ (77,002,000) $ (48,996,000)
Net loss per share:        
Net loss per share - basic $ (0.81) $ (0.70) $ (1.54) $ (1.40)
Net loss per share - diluted $ (0.81) $ (0.70) $ (1.54) $ (1.40)
Weighted average shares - basic 52,522 37,061 50,130 35,048
Weighted average shares - diluted 52,522 37,061 50,130 35,048
Other comprehensive income (loss):        
Unrealized loss on investment securities $ (1,427,000) $ (9,000) $ (3,237,000) $ (15,000)
Comprehensive loss $ (43,802,000) $ (26,104,000) $ (80,239,000) $ (49,011,000)