Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 145,548	$ 200,695
Investment securities	174,177	133,012
Prepaid expenses and other current assets	8,524	11,013
Total current assets	328,249	344,720
Property and equipment, net	2,672	2,825
Operating lease right-of-use asset	1,797	1,892
Derivative asset	68	68
Investment in Radionetics		1,010
Restricted cash	500	500
Total assets	333,286	351,015
Current liabilities:
Accounts payable and accrued expenses	12,134	8,468
Accrued compensation and related expenses	4,452	6,588
Deferred revenue	2,706
Other current liabilities	965	939
Total current liabilities	20,257	15,995
Operating lease liability, non-current	2,822	3,074
Deferred revenue, non-current	7,163
Unvested stock liability		2
Total liabilities	30,242	19,071
Commitments and contingencies (Note 7)
Stockholders’ equity:
Preferred stock, $0.001 par; 10,000 shares authorized; no shares issued or outstanding at March 31, 2022 or at December 31, 2021
Common stock and paid-in capital, $0.001 par; 200,000 shares authorized; 47,801 shares issued and outstanding at March 31, 2022; 47,598 shares issued and 47,597 shares outstanding at December 31, 2021	615,118	607,581
Accumulated other comprehensive income	(2,192)	(382)
Accumulated deficit	(309,882)	(275,255)
Total stockholders’ equity	303,044	331,944
Total liabilities and stockholders’ equity	$ 333,286	$ 351,015