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    <periodOfReport>2022-06-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001657573</issuerCik>
        <issuerName>Xometry, Inc.</issuerName>
        <issuerTradingSymbol>XMTR</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001794347</rptOwnerCik>
            <rptOwnerName>Highland Leaders Fund I, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
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            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001573958</rptOwnerCik>
            <rptOwnerName>Highland Capital Partners 9 Limited Partnership</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001573963</rptOwnerCik>
            <rptOwnerName>Highland Capital Partners 9-B Limited Partnership</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001870731</rptOwnerCik>
            <rptOwnerName>Highland Management Partners 9 LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
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            <isOfficer>0</isOfficer>
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    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001870729</rptOwnerCik>
            <rptOwnerName>HIghland Management Partners 9 Limited Partnership</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
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    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001574027</rptOwnerCik>
            <rptOwnerName>Highland Entrepreneurs' Fund 9 Limited Partnership</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
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            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001871228</rptOwnerCik>
            <rptOwnerName>Highland Leaders Fund I GP, L.P.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001871227</rptOwnerCik>
            <rptOwnerName>Highland Leaders Fund I GP, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BROADWAY</rptOwnerStreet1>
            <rptOwnerStreet2>14TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>CAMBRIDGE</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>02142</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
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                <natureOfOwnership>
                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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                    <value>See Footnote</value>
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    <footnotes>
        <footnote id="F1">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by Highland Leaders Fund I, L.P. (&quot;HLF I&quot;) to its partners.</footnote>
        <footnote id="F2">These shares are held of record by HLF I. The general partner of HLF I is Highland Leaders Fund I GP, L.P. (&quot;HLF I GP LP&quot;), whose general partner is Highland Leaders Fund I GP, LLC (&quot;HLF I GP LLC&quot;). Robert Davis, Dan Nova, Paul Maeder, Corey Mulloy and Craig Driscoll (the &quot;HLF I GP Managing Members&quot;) are the managing members of HLF I GP LLC and may be deemed to have voting and dispositive power over the shares held by HLF I. Each of HLF I GP LP, HLF I GP LLC, and the HLF I GP Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein. Mr. Driscoll is a director of the Issuer and files separate Section 16 reports.</footnote>
        <footnote id="F3">Represents a change in the form of ownership of HLF I GP LP by virtue of the receipt of shares in the pro-rata in-kind distribution of Class A Common Stock of the Issuer for no consideration by HLF I.</footnote>
        <footnote id="F4">These shares are held by HLF I GP LP. The general partner of HLF I GP LP is HLF I GP LLC. The HLF I GP Managing Members are the managing members of HLF I GP LLC. HLF I GP LLC and each of the HLF I GP Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein. Mr. Driscoll is a director of the Issuer and files separate Section 16 reports.</footnote>
        <footnote id="F5">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration by HLF I GP LP to its partners.</footnote>
        <footnote id="F6">Represents a pro-rata distribution, and not a purchase or sale, without additional consideration, by each of Highland Capital Partners 9 Limited Partnership (&quot;HCP9&quot;), Highland Capital Partners 9-B Limited Partnership (&quot;HCP9B&quot;) and Highland Entrepreneurs' Fund 9 Limited Partnership (&quot;HEF9&quot;), as applicable, to its partners.</footnote>
        <footnote id="F7">These shares are held of record by HCP9. The general partner of HCP9 is Highland Management Partners 9 Limited Partnership (&quot;HMP 9 LP&quot;),whose general partner is Highland Management Partners 9 LLC (&quot;HMP 9 LLC&quot;). Robert Davis, Dan Nova, Paul Maeder and Corey Mulloy (&quot;HMP9 Managing Members&quot;) are the managing members of HMP 9 LLC and may be deemed to have voting and dispositive power over the shares held by HCP9. Each of HMP 9 LP, HMP 9 LLC and the HMP9 Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein.</footnote>
        <footnote id="F8">These shares are held of record by HCP9B. The general partner of HCP9B is HMP 9 LP, whose general partner is HMP 9 LLC. The HMP9 Managing Members are the managing members of HMP 9 LLC and may be deemed to have voting and dispositive power over the shares held by HCP9B. Each of HMP 9 LP, HMP 9 LLC and the HMP9 Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein.</footnote>
        <footnote id="F9">These shares are held of record by HEF9. The general partner of HEF9 is HMP 9 LP, whose general partner is HMP 9 LLC. The HMP9 Managing Members are the managing members of HMP 9 LLC and may be deemed to have voting and dispositive power over the shares held by HEF9. Each of HMP 9 LP, HMP 9 LLC and the HMP9 Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein.</footnote>
        <footnote id="F10">Represents a change in the form of ownership of HMP 9 LP by virtue of the receipt of shares in the pro-rata in-kind distribution of Class A Common Stock of the Issuer for no consideration by each of HCP9, HC9B and HEF9. HMP 9 LP received (i) 22,714 of such shares in the pro-rata in-kind distribution made by HCP9, (ii) 9,784 of such shares in the pro-rata in-kind distribution made by HCP9B and (iii) 1,983 of such shares in the pro-rata in-kind distribution made by HEF9.</footnote>
        <footnote id="F11">These shares are held by HMP 9 LP. The general partner of HMP 9 LP is HMP 9 LLC. The HMP9 Managing Members are the managing members of HMP 9 LLC. Each of the HMP9 Managing Members disclaims beneficial ownership of the securities reported herein, except to the extent of their respective pecuniary interests therein, if any, and the filing of this statement shall not be deemed to be an admission that, for purposes of Section 16 of the Securities Exchange Act of 1934 or otherwise, any of them is the beneficial owner of any securities reported herein.</footnote>
        <footnote id="F12">Represents a pro-rata distribution, and not a purchase and sale, without additional consideration, by HMP 9 LP to its partners.</footnote>
    </footnotes>

    <remarks>Craig Driscoll is a member of the Issuer's board of directors and files separate Section 16 reports.</remarks>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Leaders Fund I GP, LLC, the general partner of Highland Leaders Fund I GP, L.P., the general partner of Highland Leaders Fund I, L.P.</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Management Partners 9 LLC, the general partner of Highland Management Partners 9 Limited Partnership, the general partner of Highland Capital Partners 9 Limited Partnership</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Management Partners 9 LLC, the general partner of Highland Management Partners 9 Limited Partnership, the general partner of Highland Capital Partners 9-B Limited Partnership</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Management Partners 9 LLC</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Management Partners 9 LLC, the general partner of Highland Management Partners 9 Limited Partnership</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Management Partners 9 LLC, the general partner of Highland Management Partners 9 Limited Partnership, the general partner of Highland Entrepreneurs' Fund 9 Limited Partnership</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Leaders Fund I GP, LLC, the general partner of Highland Leaders Fund I GP, L.P.</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>Jessica Healey, Authorized Officer of Highland Leaders Fund I GP, LLC</signatureName>
        <signatureDate>2022-06-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
