144 0001369900 XXXXXXXX LIVE 0001655759 Arvinas Inc 001-38672 395 Winchester Ave 5 Science Park New Haven CT 06511 475-345-3828 Noah Berkowitz Officer Common Morgan Stanley Smith Barney LLC

1 New York Plaza New York NY 100004

6022 72324.22 63960997 03/18/2026 NASDAQ Common 03/18/2026 Settlement of vested restricted stock units Arvinas, Inc N 6022 03/18/2026 Not applicable N Noah Berkowitz

396 Winchester Ave. 5 Science Park New Haven CT 06511

Common 02/13/2026 5685 67594.65 The proposed sale reported on this Form 144 will be made automatically to cover withholding taxes following the vesting of previously granted restricted stock units. The number of shares to be sold and aggregate market value are based on the closing price of common stock on March 17, 2026. The sale does not represent a discretionary trade. 03/17/2026 /s/ Jared Freedberg, as attorney-in-fact for Noah Berkowitz