144 0002026306 XXXXXXXX LIVE 0001655759 Arvinas Inc 001-38672 395 Winchester Ave 5 Science Park New Haven CT 06511 475-345-3828 Angela Cacace Officer Common Morgan Stanley Smith Barney LLC

1 New York Plaza New York NY 100004

3609 43896.77 64224294 02/23/2026 NASDAQ Common 02/23/2026 Settlement of vested restricted stock units Arvinas, Inc N 3609 02/23/2026 Not applicable N Angela Cacace

396 Winchester Ave. 5 Science Park New Haven CT 06511

Common 02/13/2026 4592 54607.52 The sale reported on this Form 144 was made automatically to cover withholding taxes following the vesting of previously granted restricted stock units. The sale does not represent a discretionary trade. 02/23/2026 /s/ Christina Bailey, as attorney-in-fact for Angela Cacace