Condensed Consolidated Statements of Changes in Stockholders' Equity (unaudited) - USD ($)	Total	Common Shares	Accumulated Deficit	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)
Balance at Dec. 31, 2019	$ 226,686,281	$ 38,461	$ (372,556,846)	$ 599,097,090	$ 107,576
Balance, Shares at Dec. 31, 2019		38,461,353
Stock-based compensation	6,119,711			6,119,711
Net loss	(21,739,171)		(21,739,171)
Restricted stock vesting		$ 129		(129)
Restricted stock vesting, Shares		128,732
Exercise of stock options	1,350,482	$ 82		1,350,400
Exercise of stock options, Shares		82,348
Unrealized loss on available-for -sale securities	(710,190)				(710,190)
Balance at Mar. 31, 2020	211,707,113	$ 38,672	(394,296,017)	606,567,072	(602,614)
Balance, Shares at Mar. 31, 2020		38,672,433
Balance at Dec. 31, 2020	642,257,512	$ 48,455	(491,888,910)	1,133,537,171	560,796
Balance, Shares at Dec. 31, 2020		48,455,741
Stock-based compensation	10,327,658			10,327,658
Net loss	(40,964,291)		(40,964,291)
Restricted stock vesting		$ 67		(67)
Restricted stock vesting, Shares		66,621
Exercise of stock options	4,480,692	$ 264		4,480,428
Exercise of stock options, Shares		263,330
Unrealized loss on available-for -sale securities	(803,551)				(803,551)
Balance at Mar. 31, 2021	$ 615,298,020	$ 48,786	$ (532,853,201)	$ 1,148,345,190	$ (242,755)
Balance, Shares at Mar. 31, 2021		48,785,692