X0306 4 2018-10-01 1 0001655759 ARVINAS INC. AVRN 0001355409 ELM STREET VENTURES L P 33 WHITNEY AVENUE NEW HAVEN CT 06510 0 0 0 1 Former 10% owner 0001754304 ELM STREET VENTURE ASSOCIATES, LLC 33 WHITNEY AVENUE NEW HAVEN CT 06510 0 0 0 1 Former 10% owner 0001754386 BETTIGOLE ROBERT A. 33 WHITNEY AVENUE NEW HAVEN CT 06510 0 0 0 1 Former 10% owner COMMON STOCK 2018-10-01 4 C 0 767623 A 767623 D On October 1, 2018, the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted into Common Stock on a 3.25-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. Elm Street Ventures, LP is the direct beneficial owner of the Common Stock. Elm Street Venture Associates, LLC is the general partner of Elm Street Ventures, LP. Robert A. Bettigole is the managing member of Elm Street Venture Associates, LLC. Elm Street Venture Associates, LLC and Robert A. Bettigole are indirect beneficial owners of the Common Stock. This Form 4 is being filed by Elm Street Ventures, LP, a Delaware limited partnership ("Elm Street"), Elm Street Venture Associates, LLC, a Delaware limited liability company ("GP"), and Robert A. Bettigole (together with Elm Street and GP, the "Reporting Persons"). /S/Robert A. Bettigole, Managing Member of Elm Street Venture Associates, LLC, the GP of Elm Street Ventures, LP 2018-10-09 /S/Robert A. Bettigole, Managing Member of Elm Street Venture Associates, LLC 2018-10-09 /S/Robert A. Bettigole 2018-10-09