X0306 4 2021-06-08 0 0001655759 ARVINAS, INC. ARVN 0001533568 Norwalk Leslie V C/O ARVINAS, INC. 5 SCIENCE PARK, 395 WINCHESTER AVE. NEW HAVEN CT 06511 1 0 0 0 Stock Option (right to buy) 78.53 2021-06-08 4 A 0 7511 0.00 A 2021-06-07 Common Stock 7511 7511 D This option award was granted on June 8, 2021. The shares underlying the award shall vest in full on June 8, 2022 or, if earlier, the date of the first meeting of the board of directors of the Issuer held after the Issuer's next annual meeting of stockholders. /s/ Matthew Batters, as attorney-in-fact for Leslie Norwalk 2021-06-10