X0306 4 2018-10-01 0 0001655759 ARVINAS INC. ARVN 0001207114 SHANNON TIMOTHY M 285 RIVERSIDE AVENUE, SUITE 250 WESTPORT CT 06880 1 0 0 0 Common Stock 2018-10-01 4 P 0 4000 16.00 A 55398 D Common Stock 2018-10-01 4 C 0 4989554 A 4989554 I See Footnote Series A Preferred Stock 2018-10-01 4 C 0 9543387 0.00 D Common Stock 2936426 0 I See Footnote Series B Preferred Stock 2018-10-01 4 C 0 4462837 0.00 D Common Stock 1373180 0 I See Footnote Series C Preferred Stock 2018-10-01 4 C 0 2209833 0.00 D Common Stock 679948 0 I See Footnote Reflects shares of the Issuer's Common Stock that were purchased in connection with the Issuer's initial public offering. On October 1, 2018, the Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted into Common Stock on a 3.25-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date. These shares are held directly by Canaan IX L.P. The Reporting Person is a non-managing member of Canaan Partners IX LLC, the general partner of Canaan IX L.P. The Reporting Person does not have voting, investment or dispositive power over any of the shares directly held by Canaan IX L.P. and disclaims beneficial ownership of the shares except to the extent of his pecuniary interest therein, if any, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the shares for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. /s/ Matthew Batters, as attorney-in-fact for Timothy M Shannon 2018-10-03