X0306 4 2019-06-06 0 0001645113 NovoCure Ltd NVCR 0001654363 Ambrogi Michael J. C/O NOVOCURE INC. 20 VALLEY STREAM PARKWAY, SUITE 300 MALVERN PA 19355 0 1 0 0 Chief Operating Officer Ordinary Shares 2019-06-06 4 M 0 5999 7.15 A 191673 D Ordinary Shares 2019-06-06 4 S 0 5999 54.786 D 185674 D Options to Buy Ordinary Shares 7.15 2019-06-06 4 M 0 5999 0.00 D 2027-02-21 Ordinary Shares 5999 103014 D Transaction was made pursuant to a Rule 10b5-1 trading plan adopted by Mr. Ambrogi. On June 6, 2019, pursuant to a Rule 10b5-1 trading plan adopted by Mr. Ambrogi, Mr. Ambrogi sold 5,999 shares in multiple trades at prices ranging from $54.49 to $55.14. The price reported above reflects the weighted average sale price. Mr. Ambrogi hereby undertakes to provide to the Staff, the issuer or any security holder of the issuer, upon request, full information regarding the number of shares and prices at which the transaction was effected. Fully vested as of the date hereof. /s/ Kimberly Burke, Attorney in fact for Michael J. Ambrogi 2019-06-10