X0306 4 2016-12-15 0 0001645113 Novocure Ltd NVCR 0001654363 Ambrogi Michael J. C/O NOVOCURE INC., 20 VALLEY STREAM PKWY SUITE 300 MALVERN PA 19355 0 1 0 0 Chief Operating Officer Ordinary Shares 2016-12-15 4 S 0 20000 9.1429 D 219084 D Ordinary Shares 2016-12-16 4 S 0 20000 8.7135 D 199084 D On December 15, 2016, pursuant to a Rule 10b5-1 trading plan adopted by Mr. Ambrogi, Mr. Ambrogi sold 20,000 shares in multiple trades at prices ranging from $9.00 to $9.375. The price reported above reflects the weighted average sale price. Mr. Ambrogi hereby undertakes to provide to the Staff, the issuer or any security holder of the issuer, upon request, full information regarding the number of shares and prices at which the transaction was effected. On December 16, 2016, pursuant to a Rule 10b5-1 trading plan adopted by Mr. Ambrogi, Mr. Ambrogi sold 20,000 shares in multiple trades at prices ranging from $8.425 to $9.15. The price reported above reflects the weighted average sale price. Mr. Ambrogi hereby undertakes to provide to the Staff, the issuer or any security holder of the issuer, upon request, full information regarding the number of shares and prices at which the transaction was effected By: /s/ Todd Longsworth, Attorney in fact for Michael J. Ambrogi 2016-12-19