Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit	Warrant
Beginning balance (in shares) at Dec. 31, 2022		67,637,351
Beginning balance at Dec. 31, 2022	$ 341,691	$ 676	$ 1,575,361	$ (983)	$ (1,233,363)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issued during period, shares, new issues (in shares)		7,986,111				2,427,693
Stock issued during period, value, new issues	134,491	$ 80	134,411			$ 24
Issuance of common stock under stock option and incentive and employee stock purchase plans (in shares)		456,597
Issuance of common stock under stock option and incentive plans	171	$ 5	166
Stock-based compensation expense	12,514		12,514
Other comprehensive income (loss)	802			802
Net loss	(49,609)				(49,609)
Ending balance (in shares) at Mar. 31, 2023		78,507,752
Ending balance at Mar. 31, 2023	440,084	$ 785	1,722,452	(181)	(1,282,972)
Beginning balance (in shares) at Dec. 31, 2022		67,637,351
Beginning balance at Dec. 31, 2022	341,691	$ 676	1,575,361	(983)	(1,233,363)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(194,900)
Ending balance (in shares) at Dec. 31, 2023		80,503,338
Ending balance at Dec. 31, 2023	350,916	$ 805	1,777,839	577	(1,428,305)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Stock issued during period, shares, new issues (in shares)						914,001
Stock issued during period, value, new issues						$ 9
Issuance of common stock under stock option and incentive and employee stock purchase plans (in shares)		741,331
Issuance of common stock under stock option and incentive plans	513	$ 7	506
Stock-based compensation expense	10,174		10,174
Other comprehensive income (loss)	(479)			(479)
Net loss	(45,083)				(45,083)
Ending balance (in shares) at Mar. 31, 2024		82,158,670
Ending balance at Mar. 31, 2024	$ 316,050	$ 821	$ 1,788,519	$ 98	$ (1,473,388)