CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Statement [Abstract]
Total revenues	$ 96,148	$ 42,087	$ 25,000
Cost and operating expenses:
Cost of sales	2,932	225	0
Research and development	257,040	198,970	157,610
Selling, General and Administrative Expense	136,253	114,082	68,116
Total cost and operating expenses	396,225	313,277	225,726
Loss from operations	(300,077)	(271,190)	(200,726)
Other income (expense):
Interest and other income, net	113	4,701	8,537
Interest expense	0	0	(67)
Total other income (expense), net	113	4,701	8,470
Net loss	$ (299,964)	$ (266,489)	$ (192,256)
Net loss per share—basic and diluted (in dollars per share)	$ (5.16)	$ (4.78)	$ (4.48)
Weighted average common shares outstanding—basic and diluted (in shares)	58,084,325	55,780,982	42,869,058
Comprehensive loss:
Net loss	$ (299,964)	$ (266,489)	$ (192,256)
Other comprehensive income (loss):
Unrealized gains (losses) on marketable securities	(278)	(100)	111
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Portion Attributable to Parent	318	0	0
Total other comprehensive income (loss)	40	(100)	111
Total comprehensive loss	$ (299,924)	$ (266,589)	$ (192,145)