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Nature of the Business and Basis of Presentation - Additional Information (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 25, 2020
USD ($)
$ / shares
shares
Feb. 19, 2020
USD ($)
$ / shares
shares
Sep. 03, 2019
USD ($)
$ / shares
shares
Aug. 19, 2019
USD ($)
$ / shares
shares
Jun. 20, 2018
USD ($)
$ / shares
shares
Jun. 11, 2018
USD ($)
$ / shares
shares
Oct. 02, 2017
USD ($)
$ / shares
shares
Feb. 29, 2020
USD ($)
$ / shares
shares
Jun. 30, 2018
USD ($)
$ / shares
shares
Oct. 31, 2017
USD ($)
$ / shares
shares
Dec. 31, 2019
USD ($)
Sep. 30, 2019
USD ($)
$ / shares
shares
Jun. 30, 2019
USD ($)
Mar. 31, 2019
USD ($)
Dec. 31, 2018
USD ($)
Sep. 30, 2018
USD ($)
Jun. 30, 2018
USD ($)
$ / shares
Mar. 31, 2018
USD ($)
Dec. 31, 2019
USD ($)
shares
Dec. 31, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Nature Of Business And Basis Of Presentation [Line Items]                                          
Share conversion ratio             5.65                            
Net loss                     $ (67,216) $ (56,196) $ (21,460) $ (47,384) $ (32,299) $ (24,435) $ (21,690) $ (21,430) $ (192,256) $ (99,854) $ (50,284)
Accumulated deficit                     (487,979)       $ (295,723)       (487,979) $ (295,723)  
Cash, cash equivalents and marketable securities                     $ 579,600               $ 579,600    
Common Shares                                          
Nature Of Business And Basis Of Presentation [Line Items]                                          
Issuance of common stock sold in public offering, net of underwriting discounts, commissions and offering costs (in shares) | shares                                     12,432,431 4,945,000 8,166,496
IPO                                          
Nature Of Business And Basis Of Presentation [Line Items]                                          
Issuance of common stock sold in public offering, net of underwriting discounts, commissions and offering costs (in shares) | shares             7,500,000     8,166,496                      
Additional offering price of common stock (in dollars per share) | $ / shares                   $ 17.00                      
Net proceeds from initial public offering             $ 114,100     $ 124,600                      
IPO | Common Shares                                          
Nature Of Business And Basis Of Presentation [Line Items]                                          
Additional offering price of common stock (in dollars per share) | $ / shares             $ 17.00                            
Follow On Offering | Common Shares                                          
Nature Of Business And Basis Of Presentation [Line Items]                                          
Issuance of common stock sold in public offering, net of underwriting discounts, commissions and offering costs (in shares) | shares     1,621,621 10,810,810 645,000 4,300,000     4,945,000     12,432,431                  
Additional offering price of common stock (in dollars per share) | $ / shares     $ 37.00 $ 37.00 $ 40.00 $ 40.00     $ 40.00     $ 37.00         $ 40.00        
Net proceeds from initial public offering     $ 56,400 $ 375,400 $ 24,300 $ 161,000     $ 185,300     $ 431,800                  
Follow On Offering | Common Shares | Subsequent Event                                          
Nature Of Business And Basis Of Presentation [Line Items]                                          
Issuance of common stock sold in public offering, net of underwriting discounts, commissions and offering costs (in shares) | shares 477,272 3,181,818           3,659,090                          
Additional offering price of common stock (in dollars per share) | $ / shares $ 55.00 $ 55.00           $ 55.00                          
Net proceeds from initial public offering $ 24,700 $ 163,700           $ 188,400