X0306 4 2023-02-15 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001713712 Flynn Daniel Lee C/O DECIPHERA PHARMACEUTICALS, INC. 200 SMITH STREET WALTHAM MA 02451 0 1 0 0 Chief Scientific Officer Common Stock 2023-02-15 4 A 0 16488 0.00 A 60183 D Common Stock 2023-02-16 4 S 0 1370 15.099 D 58813 D Common Stock 230435 I By Daniel L. Flynn Revocable Trust Common Stock 91020 I By Daniel L. Flynn Irrevocable Trust Stock Option (Right to Buy) 15.48 2023-02-15 4 A 0 65900 0.00 A 2033-02-14 Common Stock 65900 65900 D The reporting person was awarded 16,488 Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. The RSUs shall vest in three equal installments on each of February 15, 2024, February 15, 2025 and February 15, 2026. This sale was to cover tax liabilities in the vesting of restricted stock. This stock option was issued pursuant to the Issuer's 2017 Stock Option and Incentive Plan. The option shall vest in equal monthly installments over four years, beginning on March 15, 2023. /s/ Jeffrey M. Held, Attorney-in-Fact 2023-02-17