X0306 4 2022-01-18 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001325710 Sherman Matthew L C/O DECIPHERA PHARMACEUTICALS, INC. 200 SMITH STREET WALTHAM MA 02451 0 1 0 0 EVP & Chief Medical Officer Common Stock 2022-01-18 4 A 0 20500 0.00 A 77774 D Stock Option (Right to Buy) 8.27 2022-01-18 4 A 0 82000 0.00 A 2032-01-17 Common Stock 82000 82000 D The reporting person was awarded 20,500 Restricted Stock Units ("RSUs"). Each RSU represents a contingent right to receive one (1) share of the Issuer's Common Stock. The RSUs shall vest in three (3) equal annual installments on each of January 15, 2023, January 15, 2024 and January 15, 2025. This stock option was issued pursuant to the Issuer's 2017 Stock Option and Incentive Plan. The option shall vest in equal monthly installments over four (4) years, beginning on February 18, 2022. /s/ Jeffrey Held, Attorney-in-Fact 2022-01-20