X0206 3 2021-03-23 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001752827 Martin Daniel C. C/O DECIPHERA PHARMACEUTICALS, INC. 200 SMITH STREET WALTHAM MA 02451 0 1 0 0 Chief Commercial Officer Common Stock 27702 D Stock Option (Right to Buy) 36.10 2028-09-17 Common Stock 63001 D Stock Option (Right to Buy) 26.35 2029-01-29 Common Stock 45499 D Stock Option (Right to Buy) 54.87 2030-02-17 Common Stock 42190 D Stock Option (Right to Buy) 47.79 2031-02-15 Common Stock 37300 D Includes 5,280 Restricted Stock Units ("RSUs") issued pursuant to the Issuer's 2017 Stock Option and Incentive Plan (the "Plan"). The RSUs vest in three (3) equal annual installments on each of February 15, 2022, 2023 and 2024. Each RSU represents a contingent right to receive one (1) share of the Issuer's Common Stock. The RSUs may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance. Includes 8,300 RSUs issued pursuant to the Plan. The RSUs shall vest in equal annual installments over four (4) years beginning on February 15, 2022. Each RSU represents a contingent right to receive one (1) share of the Issuer's Common Stock. The RSUs may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance. This stock option, representing a right to purchase a total of 90,000 shares, was issued pursuant to the Plan. 25% of the shares became exercisable on September 18, 2019 and the remaining shares shall vest in 36 equal monthly installments thereafter, subject to continued service through such dates. This stock option, representing a right to purchase a total of 52,000 shares, was issued pursuant to the Plan. The option became exercisable in 48 equal monthly installments on January 1, 2019, subject to continued service through such dates. This stock option was issued pursuant to the Plan. The option vests in 48 equal monthly installments following the vesting commencement date of February 18, 2020, subject to continued service through such dates. This stock option was issued pursuant to the Plan. The option vests in 48 equal monthly installments following the vesting commencement date of February 16, 2021, subject to continued service through such dates. /s/ Jeffrey M. Held, Attorney-in-Fact 2021-04-02