X0306 4 2021-01-15 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001794351 Friedman Franklin Stuart C/O DECIPHERA PHARMACEUTICALS, INC. 200 SMITH STREET WALTHAM MA 02451 1 0 0 0 Stock Option (Right to Buy) 50.07 2021-01-15 4 A 0 1563 31.99 A 2031-01-14 Common Stock 1563 1563 D These options were issued upon election by the director to receive his cash board retainer fee of $50,000 for the FY 2021 in the form of an equity award, in lieu of cash, under the amended and restated non-employee director compensation policy. 391 shares will vest on March 31, 2021, 391 shares will vest on June 30, 2021, 391 shares will vest on September 30, 2021 and the remaining 390 shares will vest on December 31, 2021. /s/ Thomas P. Kelly, Attorney-in-Fact 2021-01-20