X0306 4 2018-05-17 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001533451 Hoerter Steven L. C/O DECIPHERA PHARMACEUTICALS, INC. 500 TOTTEN POND ROAD WALTHAM MA 02451 1 0 0 0 Stock Option (Right to Buy) 25.73 2018-05-17 4 A 0 24000 0.00 A 2028-05-16 Common Stock 24000 24000 D This stock option was issued pursuant to the Issuer's 2017 Stock Option and Incentive Plan. The option vests in 36 equal monthly installments following the vesting commencement date of May 17, 2018, subject to continued service through such dates. /s/ Amanda Stastny, Attorney-in-Fact 2018-05-21