X0306 4 2018-02-16 0 0001654151 Deciphera Pharmaceuticals, Inc. DCPH 0001494875 Taylor Michael Douglas C/O DECIPHERA PHARMACEUTICALS, INC. 500 TOTTEN POND ROAD WALTHAM MA 02451 1 1 0 0 See Remarks Stock Option (Right to Buy) 29.71 2018-02-16 4 A 0 225000 A 2028-02-16 Common Stock 225000 225000 D This stock option was issued pursuant to the Issuer's 2017 Stock Option and Incentive Plan. The option vests in 48 equal monthly installments following the vesting commencement date of January 1, 2018, subject to continued service through such dates. President and Chief Executive Officer /s/ Thomas P. Kelly, Attorney-in-Fact 2018-02-20