X0306 4 2020-05-21 0 0001720893 BioXcel Therapeutics, Inc. BTAI 0001653967 Votruba Michal C/O BIOXCEL THERAPEUTICS, INC., 555 LONG WHARF DRIVE NEW HAVEN CT 06511 1 0 0 0 Stock Option (Right to Buy) 49.74 2020-05-21 4 A 0 20000 0 A 2030-05-21 Common Stock 20000 20000 D Stock Option (Right to Buy) 49.74 2020-05-21 4 J 0 20000 0 D 2030-05-21 Common Stock 20000 0 D The Reporting Person immediately and automatically assigned these stock options to RSJ Investments SICAV a.s. acting in respect of its sub-fund RSJ Gradus podfund ("RSJ") pursuant to the policies of RSJ regarding stock ownership by its employees, as documented by an Agreement between the Reporting Person and RSJ. The Reporting Person does not beneficially own any of the securities reported herein. The option will vest in full and become exercisable on the earlier of the first anniversary of the grant date or the day immediately prior to the date of the next BioXcel Therapeutics, Inc. annual meeting of stockholders, subject to the Reporting Person's continued service through such vesting date. /s/ Richard I. Steinhart, Attorney-in-Fact for Michal Votruba 2020-05-26