X0306 5/A 2017-12-31 2021-04-26 0 1 0001653821 CEN BIOTECH INC CENBF 0001736911 Byrne Joseph A. 300-3295 QUALITY WAY WINDSOR, ONTARIO, CANADA A6 N8T 3R9 ONTARIO, CANADA 1 1 Chief Executive Officer* Common Stock 2017-11-30 4 A 0 L 20000 0 A 1353265 D Common Stock 2017-11-30 4 A 0 L 1250000 0 A 1353265 D 1,270,000 shares of common stock of the Issuer were granted by the issuer to the reporting person on November 30, 2017, pursuant to two restricted stock agreements pursuant to the issuer's equity compensation plan and the issuance was approved by the issuer's full board of directors. 1,353,265 shares were beneficially owned by the Reporting Person of which 76,123 shares were issuable upon conversion of a convertible note held by the Reporting Person at 12/31/2017. The reporting person served as the Chief Executive Officer and member of the Board of the Issuer from July 2017 until November 13, 2019, when the reporting person resigned from all positions with the Issuer. The reporting person was appointed as President and a member of the Board of the Issuer effective April 19, 2021. /s/ Joseph Byrne 2021-05-28