Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2025	Jun. 30, 2024
Cash flows from operating activities:
Net loss	$ (70,995)	$ (74,755)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	3,313	2,847
Stock-based compensation	15,413	20,216
Amortization of premiums and accretion of discounts on marketable securities	(3,785)	(8,537)
Amortization of right-of-use assets	1,757	1,725
Amortization of debt discount and debt issuance costs	140	0
Impairment of right-of-use assets and leasehold improvements	1,151	0
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(478)	579
Other assets	50	1,303
Accounts payable	2	643
Accrued liabilities and accrued clinical supply costs	(16,507)	(9,831)
Payable to collaboration partner	693	(1,890)
Deferred revenue	(11,548)	(30,976)
Refund liability to collaboration partner	(26,063)	(22,523)
Lease liabilities	(3,182)	(2,805)
Other long-term liabilities	210	(139)
Net cash used in operating activities	(109,829)	(124,143)
Cash flows from investing activities:
Purchase of property and equipment	(30)	(870)
Purchase of marketable securities	(131,879)	(297,769)
Maturities of marketable securities	250,385	322,163
Sale of marketable secuirities	2,981	1,857
Net cash provided by investing activities	121,457	25,381
Cash flows from financing activities:
Proceeds from issuance of common stock upon public offering, net of issuance costs	0	71,108
Purchase of common stock under employee stock purchase plan	122	644
Net cash provided by financing activities	122	71,752
Net increase (decrease) in cash, cash equivalents, and restricted cash	11,750	(27,010)
Cash, cash equivalents, and restricted cash at beginning of period	34,867	76,101
Cash, cash equivalents, and restricted cash at end of period	46,617	49,091
Non-cash investing and financing activities:
Property and equipment purchases included in accounts payable and accrued liabilities	0	185
Interest paid	$ 216	$ 0