Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 154,323	$ 329,152
Marketable securities	558,528	406,099
Receivable from Collaboration partner	2,587	7,391
Prepaid expenses and other current assets	10,997	7,071
Total current assets	726,435	749,713
Property and equipment, net	25,521	27,330
Operating lease right-of-use assets	27,811	30,569
Restricted cash	1,472	1,472
Other assets	6,409	5,574
Total assets	787,648	814,658
Current liabilities:
Accounts payable	4,189	4,749
Accrued clinical supply costs	5,559	8,748
Accrued liabilities	27,771	27,460
Deferred revenue, current portion	48,231	90,803
Operating lease liabilities, current portion	8,059	7,795
Total current liabilities	93,809	139,555
Deferred revenue, long-term portion	443,370	334,415
Operating lease liabilities, long-term portion	35,268	39,806
Other long-term liabilities	759	158
Total liabilities	573,206	513,934
Commitments and contingencies
Stockholders' equity:
Common stock, $0.0001 par value; 200,000,000 shares authorized; 82,895,718 and 81,986,192 shares issued and outstanding as of December 31, 2022 and December 31, 2021, respectively	8	8
Additional paid-in capital	798,696	748,036
Accumulated other comprehensive loss	(4,575)	(943)
Accumulated deficit	(579,687)	(446,377)
Total stockholders' equity	214,442	300,724
Total liabilities and stockholders' equity	$ 787,648	$ 814,658