Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 184,231	$ 329,152
Marketable securities	574,075	406,099
Receivable from Collaboration partner	6,491	7,391
Prepaid expenses and other current assets	10,166	7,071
Total current assets	774,963	749,713
Property and equipment, net	26,289	27,330
Operating lease right-of-use assets	28,530	30,569
Restricted cash	1,472	1,472
Other assets	5,784	5,574
Total assets	837,038	814,658
Current liabilities:
Accounts payable	4,546	4,749
Accrued clinical supply costs	5,444	8,748
Accrued liabilities	23,225	27,460
Deferred revenue, current portion	119,684	90,803
Operating lease liabilities, current portion	7,990	7,795
Total current liabilities	160,889	139,555
Deferred revenue, long-term portion	386,357	334,415
Operating lease liabilities, long-term portion	36,455	39,806
Other long-term liabilities	233	158
Total liabilities	583,934	513,934
Commitments and Contingencies
Stockholders' equity:
Common stock, $0.0001 par value; 200,000,000 shares authorized; 82,700,939 and 81,986,192 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively	8	8
Additional paid-in capital	787,097	748,036
Accumulated other comprehensive loss	(6,742)	(943)
Accumulated deficit	(527,259)	(446,377)
Total stockholders' equity	253,104	300,724
Total liabilities and stockholders’ equity	$ 837,038	$ 814,658