Condensed Consolidated Statement of Stockholders' Equity - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance at Dec. 31, 2020	$ 267,530	$ 8	$ 676,956	$ 614	$ (410,048)
Beginning balance (in shares) at Dec. 31, 2020		79,316,261
Exercise of stock options	3,874		3,874
Exercise of stock options (in shares)		415,386
Stock-based compensation	8,800		8,800
Unrealized loss on marketable securities	(204)			(204)
Net income (loss)	(52,171)				(52,171)
Ending balance at Mar. 31, 2021	227,829	$ 8	689,630	410	(462,219)
Ending balance (in shares) at Mar. 31, 2021		79,731,647
Beginning balance at Dec. 31, 2020	267,530	$ 8	676,956	614	(410,048)
Beginning balance (in shares) at Dec. 31, 2020		79,316,261
Net income (loss)	(107,318)
Ending balance at Jun. 30, 2021	184,515	$ 8	701,670	203	(517,366)
Ending balance (in shares) at Jun. 30, 2021		80,005,162
Beginning balance at Mar. 31, 2021	227,829	$ 8	689,630	410	(462,219)
Beginning balance (in shares) at Mar. 31, 2021		79,731,647
Exercise of stock options	1,993		1,993
Exercise of stock options (in shares)		207,453
Purchase of common stock under employee stock purchase plan	969		969
Purchase of common stock under employee stock purchase plan (in shares)		84,105
Forfeiture of restricted common stock		(18,043)
Stock-based compensation	9,078		9,078
Unrealized loss on marketable securities	(207)			(207)
Net income (loss)	(55,147)				(55,147)
Ending balance at Jun. 30, 2021	184,515	$ 8	701,670	203	(517,366)
Ending balance (in shares) at Jun. 30, 2021		80,005,162
Beginning balance at Dec. 31, 2021	$ 300,724	$ 8	748,036	(943)	(446,377)
Beginning balance (in shares) at Dec. 31, 2021	81,986,192	81,986,192
Exercise of stock options	$ 2,483		2,483
Exercise of stock options (in shares)		234,117
Vesting of restricted stock units		104,368
Stock-based compensation	11,939		11,939
Unrealized loss on marketable securities	(2,992)			(2,992)
Net income (loss)	(44,617)				(44,617)
Ending balance at Mar. 31, 2022	267,537	$ 8	762,458	(3,935)	(490,994)
Ending balance (in shares) at Mar. 31, 2022		82,324,677
Beginning balance at Dec. 31, 2021	$ 300,724	$ 8	748,036	(943)	(446,377)
Beginning balance (in shares) at Dec. 31, 2021	81,986,192	81,986,192
Net income (loss)	$ (34,734)
Ending balance at Jun. 30, 2022	$ 288,516	$ 8	775,843	(6,224)	(481,111)
Ending balance (in shares) at Jun. 30, 2022	81,986,192	82,544,901
Beginning balance at Mar. 31, 2022	$ 267,537	$ 8	762,458	(3,935)	(490,994)
Beginning balance (in shares) at Mar. 31, 2022		82,324,677
Exercise of stock options	41		41
Exercise of stock options (in shares)		4,244
Vesting of restricted stock units		101,076
Purchase of common stock under employee stock purchase plan	866		866
Purchase of common stock under employee stock purchase plan (in shares)		114,904
Stock-based compensation	12,478		12,478
Unrealized loss on marketable securities	(2,289)			(2,289)
Net income (loss)	9,883				9,883
Ending balance at Jun. 30, 2022	$ 288,516	$ 8	$ 775,843	$ (6,224)	$ (481,111)
Ending balance (in shares) at Jun. 30, 2022	81,986,192	82,544,901