Condensed Consolidated Balance Sheets (Unaudited) - USD ($) $ in Thousands	Jun. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 172,265	$ 329,152
Marketable securities	636,590	406,099
Receivable from Collaboration partner	8,816	7,391
Prepaid expenses and other current assets	9,350	7,071
Total current assets	827,021	749,713
Property and equipment, net	26,034	27,330
Operating lease right-of-use assets	29,226	30,569
Restricted cash	1,472	1,472
Other assets	5,919	5,574
Total assets	889,672	814,658
Current liabilities:
Accounts payable	4,646	4,749
Accrued clinical supply costs	6,142	8,748
Accrued liabilities	23,705	27,460
Deferred revenue, current portion	106,994	90,803
Operating lease liabilities, current portion	7,922	7,795
Total current liabilities	149,409	139,555
Deferred revenue, long-term portion	413,899	334,415
Operating lease liabilities, long-term portion	37,615	39,806
Other long-term liabilities	233	158
Total liabilities	601,156	513,934
Commitments and Contingencies
Stockholders' equity:
Common stock, $0.0001 par value; 200,000,000 shares authorized; 82,544,901 and 81,986,192 shares issued and outstanding as of June 30, 2022 and December 31, 2021	8	8
Additional paid-in capital	775,843	748,036
Accumulated other comprehensive loss	(6,224)	(943)
Accumulated deficit	(481,111)	(446,377)
Total stockholders' equity	288,516	300,724
Total liabilities and stockholders’ equity	$ 889,672	$ 814,658