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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Revenue:      
Total revenue $ 207,085 $ 21,098 $ 21,219
Type of Revenue [Extensible List] Collaboration Revenue [Member] Collaboration Revenue [Member] Collaboration Revenue [Member]
Operating expenses:      
Research and development $ 189,407 $ 156,869 $ 100,528
General and administrative 55,038 59,403 35,095
Total operating expenses 244,445 216,272 135,623
Loss from operations (37,360) (195,174) (114,404)
Other income, net 1,031 4,946 9,019
Net loss (36,329) (190,228) (105,385)
Unrealized gain (loss) on marketable securities (1,557) 472 184
Comprehensive loss $ (37,886) $ (189,756) $ (105,201)
Net loss per share, basic and diluted $ (0.45) $ (2.45) $ (1.71)
Shares used in computing net loss per share, basic and diluted 80,416,936 77,758,806 61,734,492