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Stock-Based Compensation - Performance-Based Restricted Stock Units (Details) - USD ($)
$ / shares in Units, $ in Millions
12 Months Ended
Mar. 20, 2017
Dec. 31, 2017
Dec. 31, 2016
Performance Based RSU      
Stock Options Granted to Non-Employees      
Shares granted (in shares) 49,332,000   0
Period from grant date during which unvested PSUs will be cancelled if milestones do not occur 3 years    
Shares outstanding (in shares)   49,332,000 0
Shares vested (in shares)   0  
Weighted average grant date fair value   $ 79.75  
Research and development expenses      
Stock Options Granted to Non-Employees      
Amount of share based compensation expense to be recognized if performance conditions are met   $ 3.9