Accrued Expenses and Other Current Liabilities (Tables)

12 Months Ended

Dec. 31, 2017

Accrued Expenses

Schedule of accrued expenses

	December 31,		December 31,
	2017		2016
Accrued manufacturing development costs	$	10,356	$	7,167
Accrued payroll, bonus and deferred compensation		9,589		3,841
Accrued construction in progress		4,156		2,979
Accrued clinical trial costs		864		389
Accrued professional and consulting fees		5,406		1,588
Accrued loss on settlement (see Note 7)		11,647		—
Other		2,920		830
Accrued expenses and other current liabilities	$	44,938	$	16,794