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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (21,940) $ (21,356)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 1,299 1,012
Loss on disposal of property and equipment 1  
Equity-based compensation 4,592 4,107
Accretion of investment discounts (1,422)  
Non-cash lease expense 218  
Changes in operating assets and liabilities:    
Accounts receivable 3,956 3,005
Prepaid expenses and other current assets (150) 1,205
Accounts payable 1,356 59
Accrued expenses (2,605) (1,609)
Deferred revenue (6,842) (4,474)
Other assets 84 318
Other long-term liabilities   (37)
Net cash used in operating activities (21,453) (17,770)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchases of property and equipment (1,533) (1,850)
Purchases of marketable securities (19,272)  
Maturities of marketable securities 26,500  
Net cash provided by (used in) investing activities 5,695 (1,850)
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from common stock offering, net of offering costs 3,639  
Proceeds from options exercised 360 6,720
Net cash provided by financing activities 3,999 6,720
Net decrease in cash and cash equivalents (11,759) (12,900)
Cash and cash equivalents, beginning of period 58,856 340,678
Cash and cash equivalents, end of period 47,097 327,778
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:    
Purchases of property and equipment unpaid at period end $ 446 $ 703