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Investments and Other Assets - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Dec. 31, 2024
Dec. 31, 2023
Schedule of Equity Method Investments [Line Items]            
Investments and other assets $ 80,243   $ 80,243   $ 44,264  
Collaboration revenue 14,245 $ 6,957 30,872 $ 35,892    
AvenCell Therapeutics, Inc. [Member]            
Schedule of Equity Method Investments [Line Items]            
Reclassification of other comprehensive income (loss) - equity method investment     2,100      
Kyverna Therapeutics Inc [Member]            
Schedule of Equity Method Investments [Line Items]            
Collaboration revenue 0   0      
AvenCell [Member]            
Schedule of Equity Method Investments [Line Items]            
Investments and other assets 7,900   7,900   7,900  
Investment Owned, Fair Value 7,900   7,900   7,900 $ 11,800
Collaboration revenue 21,000   21,000      
AvenCell [Member] | AvenCell Therapeutics, Inc. [Member]            
Schedule of Equity Method Investments [Line Items]            
Equity method investment, ownership percentage           33.33%
Sparing Vision [Member]            
Schedule of Equity Method Investments [Line Items]            
Investments and other assets 14,600   14,600   14,600  
Investment Owned, Fair Value 14,600   14,600   $ 14,600  
Collaboration revenue $ 0 $ 500 $ 0 $ 1,100