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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Income Statement [Abstract]    
Collaboration revenue $ 16,627 $ 28,935
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:    
Research and development $ 108,427 $ 111,847
General and administrative 29,007 31,091
Total operating expenses 137,434 142,938
Operating loss (120,807) (114,003)
Other income (expense), net:    
Interest income 8,603 12,632
Change in fair value of investments, net (2,125) (6,065)
Total other income , net 6,478 6,567
Net loss $ (114,329) $ (107,436)
Net loss per share, basic $ (1.1) $ (1.12)
Net loss per share, diluted $ (1.1) $ (1.12)
Weighted average shares outstanding, basic 103,500 95,502
Weighted average shares outstanding, diluted 103,500 95,502
Other comprehensive loss:    
Unrealized gain (loss) on marketable securities $ 452 $ (821)
Comprehensive loss $ (113,877) $ (108,257)