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Equity-Method Investment and Other Investments - Additional Information (Detail) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended
Oct. 31, 2021
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Dec. 31, 2022
Jul. 30, 2021
Schedule of Equity Method Investments [Line Items]              
Loss from equity method investment   $ (3,857) $ (1,834) $ (10,905) $ (7,831)    
Equity method investment   17,166   17,166   $ 32,455  
Preferred Stock Purchase Agreement [Member] | Joint Venture AvenCell [Member]              
Schedule of Equity Method Investments [Line Items]              
Equity Method Investment, Ownership Percentage             33.33%
Preferred Stock Purchase Agreement [Member] | Cellex and BXLS [Member] | Joint Venture AvenCell [Member]              
Schedule of Equity Method Investments [Line Items]              
Equity Method Investment, Ownership Percentage             66.67%
AvenCell [Member]              
Schedule of Equity Method Investments [Line Items]              
Investment Owned, at Fair Value             $ 62,900
Investments in and Advances to Affiliates, at Fair Value, Gross Reductions   3,700   8,700      
Loss from equity method investment   1,000   6,600      
Equity method investment   17,200   17,200      
Sparing Vision [Member]              
Schedule of Equity Method Investments [Line Items]              
Investment Owned, at Fair Value $ 14,800            
Sparing Vision [Member] | Series A2 Preferred Stock [Member]              
Schedule of Equity Method Investments [Line Items]              
Sale of Stock, Number of Shares Issued in Transaction 83,316            
Kyverna Therapeutics Inc [Member]              
Schedule of Equity Method Investments [Line Items]              
Investment Owned, at Fair Value   $ 10,000   $ 10,000      
Kyverna Therapeutics Inc [Member] | Series B Preferred Stock [Member]              
Schedule of Equity Method Investments [Line Items]              
Sale of Stock, Number of Shares Issued in Transaction       3,739,515      
Fair value of stock received       $ 7,000      
Number of stock additionally invested       1,602,649      
Cash consideration received on sale of common stock       $ 3,000