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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Income Statement [Abstract]        
Collaboration revenue $ 11,992 $ 13,266 $ 38,192 $ 38,548
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:        
Research and development $ 113,696 $ 96,651 $ 326,088 $ 319,945
General and administrative 29,403 22,145 87,503 66,680
Total operating expenses 143,099 118,796 413,591 386,625
Operating loss (131,107) (105,530) (375,399) (348,077)
Other income (expense), net:        
Interest income 12,740 1,945 37,373 3,188
Loss from equity method investment (3,857) (1,834) (10,905) (7,831)
Change in fair value of contingent consideration 0 (7,810) (100) (8,059)
Total other income (expense), net 8,883 (7,699) 26,368 (12,702)
Net loss $ (122,224) $ (113,229) $ (349,031) $ (360,779)
Net loss per share, basic $ (1.38) $ (1.49) $ (3.96) $ (4.78)
Net loss per share, diluted $ (1.38) $ (1.49) $ (3.96) $ (4.78)
Weighted average shares outstanding, basic 88,645 76,047 88,204 75,543
Weighted average shares outstanding, diluted 88,645 76,047 88,204 75,543
Other comprehensive loss:        
Unrealized gain (loss) on marketable securities $ 142 $ 991 $ 1,649 $ (5,069)
Other comprehensive gain (loss) from equity method investment 154 (805) 2,240 (1,667)
Comprehensive loss $ (121,928) $ (113,043) $ (345,142) $ (367,515)