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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Income Statement [Abstract]    
Collaboration revenue $ 12,606 $ 11,252
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:    
Research and development $ 97,116 $ 133,095
General and administrative 27,448 22,403
Total operating expenses 124,564 155,498
Operating loss (111,958) (144,246)
Other income (expense), net:    
Interest income 11,980 540
Loss from equity method investment (3,048) (2,745)
Change in fair value of contingent consideration (100) (421)
Total other income (expense), net 8,832 (2,626)
Net loss $ (103,126) $ (146,872)
Net loss per share, basic $ (1.17) $ (1.96)
Net loss per share, diluted $ (1.17) $ (1.96)
Weighted average shares outstanding, basic 87,772 74,751
Weighted average shares outstanding, diluted 87,772 74,751
Other comprehensive loss:    
Unrealized gain (loss) on marketable securities $ 2,989 $ (5,128)
Other comprehensive gain (loss) from equity method investment 1,794 (302)
Comprehensive loss $ (98,343) $ (152,302)