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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
shares in Thousands, $ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Income Statement [Abstract]      
Collaboration revenue $ 52,121 $ 33,053 $ 57,994
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:      
Research and development $ 419,979 $ 229,807 $ 150,408
General and administrative 90,306 71,096 44,169
Total operating expenses 510,285 300,903 194,577
Operating loss (458,164) (267,850) (136,583)
Other (expense) income, net:      
Interest income 8,542 1,283 2,352
Loss from equity method investments (11,079) (1,325) 0
Change in fair value of contingent consideration (13,485) 0 0
Total other (expense) income, net (16,022) (42) 2,352
Net loss $ (474,186) $ (267,892) $ (134,231)
Net Loss Per Share, Basic $ (6.16) $ (3.78) $ (2.40)
Net Loss Per Share, Diluted $ (6.16) $ (3.78) $ (2.40)
Weighted average shares outstanding, basic 76,972 70,894 55,987
Weighted average shares outstanding, diluted 76,972 70,894 55,987
Other comprehensive loss:      
Unrealized loss on marketable securities $ (1,637) $ (2,126) $ (260)
Other comprehensive loss from equity method investment (3,192) (507) 0
Comprehensive loss $ (479,015) $ (270,525) $ (134,491)