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Document and Entity Information - USD ($)
 12 Months Ended
Dec. 31, 2022
Feb. 17, 2023
Jun. 30, 2022
Cover [Abstract]      
Document Type 10-K    
Amendment Flag false    
Document Period End Date Dec. 31, 2022    
Document Fiscal Year Focus 2022    
Document Fiscal Period Focus FY    
Trading Symbol NTLA    
Entity Registrant Name INTELLIA THERAPEUTICS, INC.    
Entity Central Index Key 0001652130    
Current Fiscal Year End Date --12-31    
Entity Well-known Seasoned Issuer Yes    
Entity Current Reporting Status Yes    
Entity Voluntary Filers No    
Entity Filer Category Large Accelerated Filer    
ICFR Auditor Attestation Flag true    
Entity Shell Company false    
Entity Small Business false    
Entity Emerging Growth Company false    
Entity Interactive Data Current Yes    
Entity File Number 001-37766    
Entity Tax Identification Number 36-4785571    
Entity Address, Address Line One 40 Erie Street    
Entity Address, Address Line Two Suite 130    
Entity Address, City or Town Cambridge    
Entity Address, State or Province MA    
Entity Address, Postal Zip Code 02139    
City Area Code 857    
Local Phone Number 285-6200    
Entity Incorporation, State or Country Code DE    
Title of 12(b) Security Common Stock, par value $0.0001 per share    
Security Exchange Name NASDAQ    
Document Annual Report true    
Document Transition Report false    
Entity Common Stock, Shares Outstanding   88,017,939  
Entity Public Float     $ 3,889,074,263
Documents Incorporated by Reference

DOCUMENTS INCORPORATED BY REFERENCE

Part III of this Annual Report on Form 10-K incorporates by reference certain information from the registrant’s definitive Proxy Statement for its 2023 annual meeting of shareholders, which the registrant intends to file pursuant to Regulation 14A with the Securities and Exchange Commission not later than 120 days after the registrant’s fiscal year end of December 31, 2022. Except with respect to information specifically incorporated by reference in this Form 10-K, the Proxy Statement is not deemed to be filed as part of this Form 10-K.

    
Auditor Firm ID 34    
Auditor Name Deloitte & Touche LLP    
Auditor Location Boston, Massachusetts