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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Income Statement [Abstract]        
Collaboration revenue $ 13,266 $ 7,204 $ 38,548 $ 20,199
Type of Revenue [Extensible List] us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember us-gaap:LicenseAndServiceMember
Operating expenses:        
Research and development $ 96,651 $ 60,486 $ 319,945 $ 158,646
General and administrative 22,145 18,711 66,680 48,988
Total operating expenses 118,796 79,197 386,625 207,634
Operating loss (105,530) (71,993) (348,077) (187,435)
Other (expense) income, net:        
Interest income 1,945 349 3,188 780
Loss from equity method investment (1,834) 0 (7,831) 0
Change in fair value of contingent consideration (7,810) 0 (8,059) 0
Total other (expense) income, net (7,699) 349 (12,702) 780
Net loss $ (113,229) $ (71,644) $ (360,779) $ (186,655)
Net Loss Per Share, Basic $ (1.49) $ (0.97) $ (4.78) $ (2.68)
Net Loss Per Share, Diluted $ (1.49) $ (0.97) $ (4.78) $ (2.68)
Weighted average shares outstanding, basic 76,047 73,706 75,543 69,720
Weighted average shares outstanding, diluted 76,047 73,706 75,543 69,720
Other comprehensive loss:        
Unrealized gain (loss) on marketable securities $ 991 $ (161) $ (5,069) $ (175)
Other comprehensive loss from equity method investment (805) 0 (1,667) 0
Comprehensive loss $ (113,043) $ (71,805) $ (367,515) $ (186,830)