Related Party Transaction - Additional information (Detail) - USD ($) $ in Thousands	3 Months Ended		6 Months Ended
	Jun. 30, 2022	Jun. 30, 2021	Jun. 30, 2022	Jun. 30, 2021	Dec. 31, 2021	Dec. 31, 2020
Related Party Transaction [Line Items]
Revenue	$ 2,800		$ 5,700
Deferred revenue	97,136	$ 62,752	97,136	$ 62,752	$ 127,235	$ 73,931
Deferred revenue current	61,806		61,806		63,759
Deferred revenue non-current	35,330		35,330		63,476
Investment	37,128		37,128		$ 29,558
Collaboration revenue	$ 14,030	$ 6,550	$ 25,282	$ 12,995
Avencelllca
Related Party Transaction [Line Items]
Equity method investment, ownership percentage	33.33%		33.33%
Revenue	$ 5,700
Deferred revenue	37,100		$ 37,100
Deferred revenue current	34,200		34,200
Deferred revenue non-current	2,900		2,900
Avencelllca | AvenCell Co Co Agreement [Member]
Related Party Transaction [Line Items]
Deferred revenue	5,700		5,700
Avencellcoco
Related Party Transaction [Line Items]
Revenue	100		11,300
Contra Revenue			100
Kyvernalca
Related Party Transaction [Line Items]
Deferred revenue	5,000		5,000
Investment	10,000		10,000
Collaboration revenue	$ 2,000		$ 2,000