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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Follow On Public Offering
At The Market Offerings
Regeneron Pharmaceuticals Inc. [Member]
Cumulative Effect, Period of Adoption, Adjustment [Member]
Follow-on Offering [Member]
Follow-on Offering [Member]
Follow On Public Offering
Follow-on Offering [Member]
At The Market Offerings
Follow-on Offering [Member]
Regeneron Pharmaceuticals Inc. [Member]
Additional Paid-In Capital [Member]
Additional Paid-In Capital [Member]
Follow On Public Offering
Additional Paid-In Capital [Member]
At The Market Offerings
Additional Paid-In Capital [Member]
Regeneron Pharmaceuticals Inc. [Member]
Accumulated Other Comprehensive (Loss) Income [Member]
Accumulated Deficit [Member]
Accumulated Deficit [Member]
Cumulative Effect, Period of Adoption, Adjustment [Member]
Beginning balance at Dec. 31, 2018 $ 277,920         $ 5       $ 478,968       $ (28) $ (201,025)  
Beginning balance (ASC 842 [Member]) at Dec. 31, 2018         $ (320)                     $ (320)
Beginning balance, shares at Dec. 31, 2018           45,224,480                    
Issuance of common stock     $ 72,256                 $ 72,256        
Issuance of common stock, shares               4,518,579                
Exercise of stock options 3,086                 3,086            
Exercise of stock options, shares           364,404                    
Issuance of shares under employee stock purchase plan 1,092                 1,092            
Issuance of shares under employee stock purchase plan, shares           90,581                    
Equity-based compensation 15,091                 15,091            
Equity-based compensation, shares           0                    
Other comprehensive income - unrealized gain (loss) on marketable securities 289                         289    
Net loss (99,533)                           (99,533)  
Ending balance at Dec. 31, 2019 269,881         $ 5       570,493       261 (300,878)  
Ending balance, shares at Dec. 31, 2019           50,198,044                    
Issuance of common stock   $ 296,607 49,461 $ 12,580     $ 2       $ 296,605 49,461 $ 12,580      
Issuance of common stock, shares             11,815,069 2,270,161 925,218              
Exercise of stock options 11,574                 11,574            
Exercise of stock options, shares           840,824                    
Vesting of restricted stock units, shares           82,829                    
Issuance of shares under employee stock purchase plan 1,557                 1,557            
Issuance of shares under employee stock purchase plan, shares           101,911                    
Equity-based compensation 19,903                 19,903            
Other comprehensive income - unrealized gain (loss) on marketable securities (260)                         (260)    
Net loss (134,231)                           (134,231)  
Ending balance at Dec. 31, 2020 $ 527,072         $ 7       962,173       1 (435,109)  
Ending balance, shares at Dec. 31, 2020 66,234,056         66,234,056                    
Issuance of common stock   $ 648,315 $ 45,255               $ 648,315 $ 45,255        
Issuance of common stock, shares             4,758,620 641,709                
Exercise of stock options $ 41,094                 41,094            
Exercise of stock options, shares 2,700,886         2,700,886                    
Vesting of restricted stock units, shares           119,715                    
Issuance of shares under employee stock purchase plan $ 2,024                 2,024            
Issuance of shares under employee stock purchase plan, shares           30,897                    
Equity-based compensation 47,009                 47,009            
Other comprehensive income - unrealized gain (loss) on marketable securities (2,126)                         (2,126)    
Other comprehensive loss - equity method investment (507)                         (507)    
Net loss (267,892)                              
Ending balance at Dec. 31, 2021 $ 1,040,244         $ 7       $ 1,745,870       $ (2,632) $ (703,001)  
Ending balance, shares at Dec. 31, 2021 74,485,883         74,485,883