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Related Party Transactions - Additional Information (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Related Party Transaction [Line Items]
Deferred revenue	$ 127,235,000	$ 73,931,000	$ 28,810,000
Deferred revenue current	63,759,000	22,544,000
Deferred revenue non-current	63,476,000	51,387,000
Investments and Other Noncurrent Assets	$ 29,558,000	$ 4,748,000
AvencellLca
Related Party Transaction [Line Items]
Investment Percentage	33.33%
Deferred revenue	$ 54,100
Deferred revenue current	34,200
Deferred revenue non-current	19,900
Revenue	5,900
AvencellCoCo
Related Party Transaction [Line Items]
Revenue	200
KyvernaLca
Related Party Transaction [Line Items]
Investments and Other Noncurrent Assets	$ 10,000.0