Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands		12 Months Ended
	Mar. 27, 2020	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income Tax Benefit [Line Items]
Net operating loss carryforwards, federal		$ 800,500	$ 372,500
Taxable Income available for the period the loss was generated		20 years
Percentage of Coronavirus Aid Relief and Economic Security Act removes the limit for taxable years	80.00%
Coronavirus Aid Relief and Economic Security Act allows net operating losses carryback period	5 years
Increase in valuation allowance		$ 163,900	42,400	$ 34,500
Research and development and other credit		61,698	23,166
Unrecognized tax benefits		$ 0
Operating Loss Carryforward Indefinitely Begins to Expire in 2034 [Member]
Income Tax Benefit [Line Items]
Net operating loss carryover, percentage of taxable income		100.00%
Operating Loss Carryforward Indefinitely [Member]
Income Tax Benefit [Line Items]
Net operating loss carryover, percentage of taxable income		80.00%
Federal [Member]
Income Tax Benefit [Line Items]
Net operating loss carryforwards, expiration date description		begin to expire in 2034
Net operating loss carryforwards, begins to expiring year		2034
Tax credit carryforwards, expiration date description		begin to expire in 2034
Tax credit carryforwards, begins to expiring year		2034
Federal [Member] | Operating Loss Carryforward Indefinitely Begins to Expire in 2034 [Member]
Income Tax Benefit [Line Items]
Net operating loss carryforwards, with expiration date		$ 37,200
Federal [Member] | Operating Loss Carryforward Indefinitely [Member]
Income Tax Benefit [Line Items]
Net operating loss carryforwards with no expiration date		763,300
Federal [Member] | Tax Carryforwards Begin to Expire in 2034 [Member]
Income Tax Benefit [Line Items]
Tax credit carryforwards, with expiration date		$ 37,900	15,000
State [Member]
Income Tax Benefit [Line Items]
Net operating loss carryforwards, expiration date description		begin to expire in 2034.
Net operating loss carryforwards, begins to expiring year		2034
Research and development and other credit		$ 30,200	10,300
Research and development tax credits, expiration year		2029
Research and development tax credits, expiration date description		begin to expire in 2029
State [Member] | Operating Loss Carryforward Begin to Expire In 2034 [Member]
Income Tax Benefit [Line Items]
Net operating loss carryforwards, with expiration date		$ 767,800	$ 373,100