Accrued Expenses - Schedule of Accrued Expenses (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Payables and Accruals [Abstract]
Employee compensation and benefits	$ 20,359	$ 10,920
Accrued research and development	16,979	11,008
Accrued legal and professional expenses	3,100	1,876
Accrued other	2,871	1,750
Total accrued expenses	$ 43,309	$ 25,554