X0306 4 2023-03-07 0 0001651944 DermTech, Inc. DMTK 0001787176 Dobak John C/O DERMTECH, INC. 11099 N. TORREY PINES ROAD, SUITE 100 LA JOLLA CA 92037 1 1 0 0 Chief Executive Officer Common Stock 2023-03-07 4 S 0 709 4.06 D 667091 D Common Stock 2023-03-07 4 S 0 23246 4.06 D 643845 D The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on March 29, 2021. Includes 5 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2022 and 2,500 shares acquired under the Issuer's Employee Stock Purchase Plan on February 28, 2023. The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on March 25, 2022. /s/ Mo Tashakor, attorney-in-fact 2023-03-09