X0306 4 2023-03-07 0 0001651944 DermTech, Inc. DMTK 0001701970 Sun Kevin M C/O DERMTECH, INC. 11099 N. TORREY PINES RD. SUITE 100 LA JOLLA CA 92037 0 1 0 0 Chief Financial Officer Common Stock 2023-03-07 4 S 0 198 4.06 D 225203 D Common Stock 2023-03-07 4 S 0 8489 4.06 D 216714 D Common Stock 2023-03-07 4 A 0 85114 0.00 A 301828 D Common Stock 2023-03-08 4 S 0 3020 3.88 D 298808 D The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on March 29, 2021. Includes 2,500 shares acquired under the Issuer's Employee Stock Purchase Plan on February 28, 2023. The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on March 23, 2022. The securities awarded are in the form of restricted stock units issued pursuant to the issuer's 2020 Equity Incentive Plan. Each restricted stock unit represents a contingent right to receive one share of issuer common stock. Subject to the reporting person's continued service, (i) three thirty-sixths (3/36) of the restricted stock units shall vest on June 5, 2023 and (ii) the remaining thirty-three thirty-sixths (33/36) shall vest in eleven (11) equal installments of three thirty-sixths (3/36) on the fifth day of each third month following June 5, 2023 until the final vesting date on March 5, 2026. The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on January 17, 2020. /s/ Mo Tashakor, attorney-in-fact 2023-03-09