X0306 4 2021-09-08 0 0001651944 DermTech, Inc. DMTK 0001807311 Ibarra Claudia C/O DERMTECH, INC. 11099 N. TORREY PINES RD. SUITE 100 LA JOLLA CA 92037 0 1 0 0 Chief Operating Officer Common Stock 2021-09-08 4 S 0 3020 36.18 D 114566 D The shares were sold by the reporting person to generate proceeds used to satisfy the tax withholding obligation that arose upon the vesting of certain restricted stock units granted to the reporting person on January 17, 2020. Includes 359 shares acquired under the Issuer's Employee Stock Purchase Plan on August 31, 2021. /s/ Jason S. Miller, attorney-in-fact 2021-09-10